Symptoms Ease
Energy and focus start to return as your blood iron stabilizes - but your storage tank is still nearly empty.
ProbIron is a gentle iron wellness blend designed to support healthy iron levels as part of your daily routine.
Clinically studied iron bisglycinate - the most bioavailable, best-tolerated form.
Reformulated to contain 10 Billion Lp299v, the most clinically studied probiotic strain shown to support iron absorption and gut health simultaneously.
Gentle on your stomach - no nausea, no constipation, better compliance.
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"Iron deficiency is incredibly common in women with PCOS, especially those with heavy periods. But most iron supplements cause terrible digestive side effects that lead women to stop taking them. ProbIron solves this with a gentle, absorbable form paired with probiotics for gut support."
601+ clinicians recommend this formula
Take our free 2-minute comprehensive women's hormonal wellness assessment to see how your symptoms map to a personalised protocol.
If you're exhausted no matter how much you sleep, if your brain feels foggy by noon, if you get dizzy when you stand up too fast - you might be iron deficient. And if you've tried iron supplements before and given up because of the stomach pain, constipation, and nausea - you're not alone.
For women with PCOS, heavy or irregular periods can drain iron stores faster than your diet can replace them. Low iron doesn't just make you tired. It impairs thyroid function, reduces exercise tolerance, affects mood, and makes every other PCOS symptom feel harder to manage.
ProbIron was formulated to solve the iron supplement dilemma. Iron bisglycinate is chelated to the amino acid glycine, making it dramatically more absorbable and gentler on your digestive system. Add targeted probiotics that support both iron absorption and gut health, and you have an iron supplement you can actually stick with.
"ProbIron is gentle and easy to take daily. I love that it fits into my morning routine."
"Finally an iron supplement that's gentle on my stomach. Easy to stay consistent with every day."
Individual results may vary.
New Formula
We rebuilt ProbIron around Lp299v - the specific probiotic strain and dose used in the published human iron-absorption research.
| ProbIron v2Lp299v, 10B CFU | Original ProbIronL. plantarum, 2B CFU | Typical Ferrous SulfateStandard iron salt | |
|---|---|---|---|
| Strain | Lp299v - the specific clinically studied strain | Generic L. plantarum | No probiotic |
| Dose | 10 billion CFU | 2 billion CFU | No probiotic |
| Iron absorption evidence | Matches the dose used in the human absorption trials cited below | Not strain-specific | Relies on iron salt alone |
| Studied in | Menstruating women, iron-deficient female athletes, pregnancy | - | - |
| Common GI side effects | Gentler, lower elemental iron load | Possible | Frequently reported (constipation, nausea, cramping) |
These statements refer to published research on Lp299v generally, not this specific finished product. This product is not intended to diagnose, treat, cure, or prevent any disease.
Human Clinical Evidence
We didn't pick Lp299v because it's trendy. We picked it because it's the only probiotic strain with repeated, peer-reviewed human trials proving it helps women absorb more iron - at the exact 10 billion CFU dose we use inside every ProbIron capsule.
+29%
More iron absorbed
Iron absorption rose from 17.4% to 22.3% when Lp299v was taken with an iron meal vs the same meal without it (p < 0.05).
Hoppe et al., PLOS ONE, 2017 - freeze-dried Lp299v, menstruating women
+66%
Larger ferritin gain vs iron alone
In iron-deficient female athletes, 4 weeks of Lp299v + 20 mg iron raised ferritin +13.6 µg/L vs +8.2 µg/L with 20 mg iron alone.
Axling et al., Nutrients, 2020 - RCT, iron-deficient female athletes
326
Pregnant women studied
A randomized clinical trial in 326 healthy pregnant women showed Lp299v paired with a low dose of iron helped maintain iron status through pregnancy.
Axling et al., Acta Obstet Gynecol Scand, 2021
30+ yrs
Of clinical documentation
Lp299v is the most clinically documented Lactiplantibacillus plantarum strain in the world, with iron-absorption benefits reviewed by EFSA in 2016.
EFSA Journal, 2016; Probi LP299V® scientific dossier
The published dose matters. Every human iron-absorption trial that showed a benefit used 10 billion CFU (10¹⁰) of freeze-dried Lp299v - the same dose in ProbIron v2. The prior formula delivered 2 billion CFU of a generic L. plantarum, which has never been studied for iron absorption.
Statistics above describe the published research on Lactiplantibacillus plantarum 299v as a strain. They are not claims about this finished product. This product is not intended to diagnose, treat, cure, or prevent any disease.
Iron and gut support that actually works together.
Iron bisglycinate supports healthy hemoglobin and oxygen delivery as part of a balanced daily routine.
Chelated iron plus probiotics means effective iron supplementation without digestive distress.
Replenishes iron stores depleted by heavy or irregular periods common in PCOS.
Targeted probiotic strains support digestive comfort and enhance nutrient absorption.
Iron supports everyday wellness, including mental clarity, as part of your daily nutrition.
Iron bisglycinate supports healthy hemoglobin and oxygen delivery as part of a balanced daily routine.
Chelated iron plus probiotics means effective iron supplementation without digestive distress.
Replenishes iron stores depleted by heavy or irregular periods common in PCOS.
Targeted probiotic strains support digestive comfort and enhance nutrient absorption.
Iron supports everyday wellness, including mental clarity, as part of your daily nutrition.
Real change happens gradually. Here's what 50,000+ women have experienced.
You'll notice the difference immediately - no stomach pain, no constipation, no nausea. Your body begins absorbing iron efficiently thanks to the bisglycinate form and vitamin C co-factor.
Many women begin noticing improved energy, less brain fog, and fewer episodes of dizziness. Exercise feels less exhausting. Your body is rebuilding its iron stores.
Ferritin levels climb into healthy ranges. Women report sustained energy throughout the day, clearer thinking, better mood, and improved exercise tolerance. The exhaustion that once felt permanent lifts.
Individual results may vary. Timeline based on customer-reported experiences.
Feeling better is just the beginning. Your body needs a sustained, daily supply of iron to refill the deep storage (ferritin) it draws from - and that rebuild simply can't be rushed. Stopping early is the #1 reason iron levels rebound.
Energy and focus start to return as your blood iron stabilizes - but your storage tank is still nearly empty.
With consistent daily intake, your body shifts from surviving to rebuilding. Ferritin slowly climbs.
Ferritin reaches healthy ranges. This is the point most women stop too early without a steady supply on hand.
Iron repletion is a marathon, not a sprint. A subscription ensures you have a steady supply for the full 3+ months it takes to rebuild your stores - delivered automatically, at the lowest price.
I created ProbIron because I was tired of being told to "just take iron" when every iron supplement made me feel worse than the deficiency.
After years of heavy periods from PCOS, my ferritin dropped to single digits. I was exhausted, foggy, and dizzy. My doctor prescribed iron, but every form I tried - ferrous sulfate, ferrous fumarate, liquid iron - caused unbearable stomach cramps and constipation. I'd take it for a week, feel miserable, and stop.
It was a vicious cycle: too iron-depleted to function, but unable to tolerate the supplements that were supposed to help. I knew there had to be a better way.
ProbIron uses iron bisglycinate, the most bioavailable and gentle form of iron available. We added targeted probiotics that support both iron absorption and the gut health that traditional iron supplements destroy. And we included vitamin C and methylfolate to maximize absorption and support healthy red blood cell production.
Because you shouldn't have to choose between building your energy and destroying your gut.
We don't do filler. Every ingredient is clinically researched and included at effective doses.
*These statements refer to published research on individual ingredients, not this specific product. This product is not intended to diagnose, treat, cure, or prevent any disease.
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Real hormonal change is a gradual process, not an overnight fix. A woman's body works in cycles that unfold over months, so the most meaningful benefits of any supplement show up when you give it consistent time. That's why we encourage at least 3 months of daily use before judging the results.
The egg you release this month started maturing around 90 to 100 days ago. Nutritional support you give your body today is laying the groundwork for cycles you won't see for months.
Female hormones move in monthly rhythms, not days. It typically takes three or more complete cycles for the body to find a steadier, more balanced pattern.
Supplementation works by gently replenishing what the body draws on every day. Those reserves are restored steadily with consistent daily use, not in a single dose.
Consistency is the real secret. Taking your supplements every day for three months or more gives your hormones the steady support they need to find their natural rhythm.
ProbIron is one of four formulas in our Motherhood Wellness Bundle - complete nutritional support for before, during, and after pregnancy. Gentle iron to fight fatigue, plus prenatal, cycle, and omega support in one simple routine.
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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. Consult your healthcare provider before starting any supplement regimen, especially if you are pregnant, nursing, or taking medication.